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What to expect at ASH 2017?

News Published on December 8, 2017

The 59th Annual Meeting & Exposition of the American Society of Hematology will be hosted in Atlanta from the 9th to the 12th of December 2017, for another exciting round of stimulating discussions and presentations of results in the malignant and non-malignant Hematology field.

ASH 2017 Abstracts ta-Scan

Top 10 Therapeutic Areas

Unsurprisingly, Leukemia will be the hottest topic at this year’s ASH meeting, followed by LymphomaAnemia, and Multiple Myeloma. Other presentations will cover research about HemorrhageMyelodysplastic Syndromes and other Blood Coagulation Disorders, in which the interest has remained stable over the past 3 years.

ASH 2017 Top 10 Therapeutic Areas ta-Scan

Top 15 Commercial Sponsors Trials over the Last 3 Years

From a trial perspective, you can expect considerable differences in trial discussion activity compared to the past 2 years. With an increase of almost 70% in presentations about trials (427 trials in 2017, compared to 255 trials in 2015), the 59th ASH meeting has 323 new trials in store for its attendees. This trend confirms the commitment of several sponsors to stay ahead and relevant in the field of Hematology.

ASH 2017 Top 15 Commercial Sponsors Trials ta-Scan

Most impressive is the increase in trials sponsored by Roche and Johnson & Johnson. Out of the 30 trials Johnson & Johnson is sponsoring this year, half of them are researching Daratumumab in combination with other drugs in Multiple Myeloma, as well as other indications. Roche, on the other hand, is studying combination therapies with Obinutuzumab, mainly in Leukemia and Lymphoma.

ASH 2017 Growing Sponsors ta-Scan

Drugs of Interest

Burton’s Tyrosine Kinase Inhibitors (BTK Inhibitors) and CD19 CARTs are still among the preferred modes of action to target in drug development.ASH 2017 Drugs of Interest ta-Scan

With 3 new molecules and 4 trials in Leukemia and Lymphoma, DTRM Biopharma is one of the smaller sponsors that is betting on BTK inhibitors.

Over the past few years, CD19 is also growing in importance as a target in Leukemia with CART-T therapies. With new drugs in development by ADC-Therapeutics, Kite Pharmaceuticals, and Celgene, we expect a competitive battle for market share in Leukemia.

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